Call for Abstract

4th International Conference on Diabetes and Cholesterol Metabolism, will be organized around the theme ““Preventive Health Care Measures for Metabolic Disease””

METABOLIC DISEASES 2021 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in METABOLIC DISEASES 2021

Submit your abstract to any of the mentioned tracks.

Register now for the conference by choosing an appropriate package suitable to you.

The study of endocrine system, its diseases, and its specific secretions (hormones) is known as Endocrinology. The secreted hormones stimulate many body functions such as regulating breathing, fluid balance, feminization, appetite, weight control, bones, and tissues growth. Endocrine system plays an important role in regulating secretions in the body.  Endocrine diseases relates to excess or limited secretion of hormones or difficulties with receiving the hormone. Most common endocrine disorders are diabetes mellitus, Graves’ disease, acromegaly, Hashimoto’s thyroiditis, hypothyroidism, hyperthyroidism, Addison’s disease, and Cushing’s syndrome. The endocrine disorders have widespread symptoms, affect various parts of the body, and can vary in severity from mild to very severe. The treatment of endocrine disorders often relays on adjusting hormone balance using synthetic hormones. If endocrine disorders are left untreated it leads to many complications throughout the body.

  • Track 1-1Cellular Endocrinology
  • Track 1-2Comparative Endocrinology
  • Track 1-3Endocrine Oncology
  • Track 1-4Neuroendocrinology

Metabolism is the set of physical and chemical processes that takes place in an organism by which its material substance is produced, maintained, and destroyed, and by which energy is made available. Metabolism aids in the conversion of food to energy and run cellular processes; to build proteins, lipids, nucleic acids, and some carbohydrates; and the elimination of metabolic wastes. When the metabolism process fails to function properly it leads to metabolic disorders. The body needs amino acids and proteins to perform all functions. Metabolic disorders can occur due to abnormal chemical reactions that help metabolic process, nutrition deficiency, loss of an enzyme that is essential for metabolic process, or due to disease in liver, pancreas, and endocrine glands. Few classes of metabolic disorders are:

  • Track 2-1Disorders of calcium metabolism
  • Track 2-2Metabolic brain diseases
  • Track 2-3DNA repair-deficiency disorders
  • Track 2-4Glucose metabolism disorders
  • Track 2-5Iron metabolism disorders
  • Track 2-6Inborn error of metabolism
  • Track 2-7Metabolic syndrome X
  • Track 2-8Malabsorption syndromes

Cholesterol is an important lipid for mammalian cells and its homeostasis is strongly regulated. Any disturbance in homeostasis of cellular cholesterol leads to atherosclerosis and cardiovascular diseases. Endoplasmic reticulum (ER) plays an important role in maintaining cholesterol metabolism and homeostasis. High levels of glucose, fat, and cholesterol in the blood can lead to atherosclerosis, vessel dysfunction and blocked blood flow, the principal mechanism for cardiovascular diseases (CVDs). CVDs comprise stroke, heart attack and peripheral arterial disease (PAD) among others.  A high level of cholesterol in blood leads to Hypercholesterolemia and people with hypercholesterolemia have more chances of developing coronary artery disease.  Presence of very low levels of cholesterol in blood leads to hypocholesterolemia. This can be due to decreased liver function, malnutrition, hyperthyroidism, intestinal loss, Addison’s-like disease

  • Track 3-1Arcus Cornealis
  • Track 3-2Hypoadrenocorticism
  • Track 3-3Xanthelasmata
  • Track 3-4Porto-systemic shunts
  • Track 3-5Inflammatory bowel disease

Abnormal lipid profiles are shown by patients with polygenic disorders as hormone regulates several steps of lipid metabolism. Patients suffering with Type1 diabetes show adequate glycaemic control but do not have quantitative lipoprotein abnormalities. Studies shows that patients with both type 1 and type 2diabetes have consistent weight gain, exhibited more lipid profiles in Type2 diabetes (T2D). Dyslipidaemia in Type2 diabetes has shown many strictly linked abnormalities.

  • Track 4-1Diabetes control and complications
  • Track 4-2Hyperglycemia and insulin resistance
  • Track 4-3Dyslipidemia

Metabolic syndrome is a mixture of many risk factors which comprises hyperglycemia, high blood pressure, abnormal cholesterol levels and excess body fat around the waist. These factors double the risk of heart disease, stroke, and diabetes.  This disorder is also known by other terms like Syndrome X, dysmetabolic syndrome and insulin resistance syndrome. Insulin resistance, metabolic syndrome and prediabetes have overlying features and are closely related to one another. Most of the disorders accompanied with metabolic syndrome have no symptoms, even though it is closely connected to insulin resistance, overweight or obesity and inactivity. Metabolic syndrome can be prevented or reversed by adopting a healthy lifestyle, including regular exercise, losing weight, healthy diet, stopping smoking, and alcohol.

  • Track 5-1Abdominal obesity
  • Track 5-2Proinflammatory state
  • Track 5-3Insulin resistance
  • Track 5-4Atherogenic dyslipidemia
  • Track 5-5Raised blood pressure

Metabolic brain disorders are deleterious metabolic disorders that are usually associated with acute and severe illness. Although the metabolic brain disorders are very rare, acquired or inborn metabolic diseases leads to brain dysfunction or damage. These are classified as primary and secondary metabolic disorders that adversely affect cerebral function. These disorders are categorized as amino acid metabolism disorders, organic acid disorders, primary lactic acidosis, or fatty acid oxidation disorders.

  • Track 6-1Wernicke’s encephalopathy
  • Track 6-2Subacute combined degeneration
  • Track 6-3Osmotic myelinolysis syndrome
  • Track 6-4Hepatic encephalopathy

Many metabolic disorders affect liver and causes chronic liver diseases, leading to cirrhosis and liver cancer. The most common metabolic liver disease are hereditary hemochromatosis, Alpha-I antitrypsin deficiency (AATD), and Wilson Disease. Metabolic liver diseases might be due to excess iron load or copper load, or some rare genetic conditions that causes emphysema in adults or liver disease at any age. Treatment for metabolic liver diseases include:

  • Track 7-1Therapeutic phlebotomy
  • Track 7-2Liver transplantation
  • Track 7-3Proper nutrition

Reproductive endocrinology and infertility is a part of gynecology and obstetrics which educates physicians of reproductive medicine about hormonal functioning as it connects to reproduction as well as the issue of infertility. The specialists in the field of REI focus on treating infertility, while reproductive endocrinologists are trained to test and treat hormonal dysfunctions in females and males. Reproductive surgery physician are even given training to operate on anatomical disorders that affect fertility.

  • Track 8-1Laparoscopy
  • Track 8-2Hysteroscopy
  • Track 8-3Abdominal myomectomy
  • Track 8-4Intra Uterine Insemination (IUI)
  • Track 8-5In Vitro Fertilization (IVF)

Pediatric metabolic disorders are observed in children when their body is not properly processing the nutrients like sugars, proteins, or fats. The metabolic disorders seen in children can be genetic that is passed down in families. If the metabolic disorders are seen in older children then it is often due to obesity. Children with metabolic disorders are at greater risk to develop diseases such as Type 2 diabetes and heart disease.

  • Track 9-1Galactosemia
  • Track 9-2Homocystinuria
  • Track 9-3Phenylketonuria (PKU)
  • Track 9-4Fatty acid oxidation disorders (including MCAD, LCHAD, VLCAD)

It was estimated that 460 million people had diabetes and resulted in about 4.2 million deaths worldwide in the year 2019. Diabetes mellitus is carbohydrate metabolism disorder characterized by high blood glucose levels (hyperglycemia). There are 2 types of diabetes mellitus one resulting from inadequate production of the insulin hormone (type 1 diabetes), and other due to an ineffective response of cells to insulin (type 2 diabetes). If patient is left untreated, diabetes can lead to many health complications. Type 1 diabetes can be managed by injections of insulin, whereas, type 2 diabetes (most common type of diabetes), can be managed by following a healthy life style. Some serious complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, nerve and eye damage and cognitive impairment.

  • Track 10-1Type 1 Diabetes Type2 Diabetes and Its Treatment
  • Track 10-2Gestational diabetes
  • Track 10-3Genetics of Diabetes
  • Track 10-4Diabetic Heart Diseases and Management
  • Track 10-5Diabetic Eye Complications
  • Track 10-6Diabetic Neuropathy and Nephropathy
  • Track 10-7Insulin and Beta Cell Targeting
  • Track 10-8Epidemiology of diabetes
  • Track 10-9Metabolic changes in diabetes
  • Track 10-10Diabetic encephalopathy
  • Track 10-11Hyperglycemia and Hypoglycemia

Gestational diabetes is a type of diabetes seen in pregnant women due to high blood glucose levels in their body. This is because of the body’s inability to use up all the insulin needed to support the demands of the pregnancy.  Even though pregnant women experience gestational diabetes only 7% women face complications due to it. It increases risk of type 2 diabetes. High glucose levels in blood is not only a concern for mothers health, but it also leads to long term complication in new born if left untreated. Gestational Diabetes can be treated by

  • Track 11-1Proper diet
  • Track 11-2Doing Physical activities
  • Track 11-3Medication
  • Track 11-4Monitor blood sugar levels regularly

Diabetic retinopathy is an eye complication seen in people suffering from diabetes. This is observed when high blood sugar levels damage the blood vessels in the retina, causing swelling, leakage, and blood flow, resulting in loss of vision. Various surgical procedures for glaucoma are Argon laser trabeculoplasty (ALT), Selective laser trabeculoplasty (SLT), Laser peripheral iridotomy (LPI), Cyclophotocoagulation, Trabeculectomy, Drainage implant surgery, and Electrocautery. Various diabetic retinopathy surgical procedures are Photocoagulation, Panretinal photocoagulation, Vitrectomy, Injecting medicine into the eye. Diabetic eye complications can be identified by symptoms like

  • Track 12-1Blurred vision
  • Track 12-2Spots or dark strings floating in your vision (floaters)
  • Track 12-3Fluctuating vision
  • Track 12-4Impaired color vision
  • Track 12-5Dark or empty areas in your vision
  • Track 12-6Vision loss

Patients suffering with diabetes are more susceptible for oral health complications than normal people whose blood glucose levels are in control. Diabetes is also a reason for many dental and gum diseases like gingivitis, periodontitis (mild and severe), fungal infections, dry mouth, loose teeth and so on. Balancing Blood glucose levels and maintaining proper oral and dental hygiene helps to reduce such oral complications.

  • Track 13-1Oral manifestations of diabetes
  • Track 13-2Dental
  • Track 13-3Diabetes mellitus
  • Track 13-4Oral health

Inherited Metabolic Errors are a diverse group of disorders that are genetically transmitted, typically in an autosomal recessive fashion, may occur as the result of spontaneous mutations. These diseases ultimately results to defects in the biochemical pathways involved in either the break-down or storage of carbohydrates, fatty acids, and proteins. 

  • Track 14-1Carbohydrate metabolism disorder
  • Track 14-2Organic acid disorders
  • Track 14-3Urea cycle defects
  • Track 14-4Amino acid disorders

Obesity is a chronic metabolic disorder that affects both children and adults globally. It is the major risk factor for a number of non-communicable diseases, mainly in type 2 diabetes. Obese people with impaired glucose tolerance (IGT) or impaired fasting glucose (IFG) should take care of their body weight to prevent further progression to diabetes.  Patients older than 45 years are screened for body mass index (BMI) to determine diabetes.

  • Track 15-1Obesity and type 1 diabetes
  • Track 15-2Obesity and type 2 diabetes
  • Track 15-3Obesity and insulin resistance
  • Track 15-4Diabetes mellitus and obesity

Endocrine oncology is a medical speciality that deals with hormone producing tumors, i.e. a combination of endocrinology and oncology. Neuroendocrine tumors are neoplasms that arise from endocrine and nervous cells. Most commonly seen tumors are carcinoid tumors that affect the intestine, but there are other types of cancers that affect pancreas, lung and the rest of the body. Even though there are many types of  NETs, all are treated as a group of tissue, as the cells of these neoplasms share common features like looking similar,  some special secretory granules, and often produce biogenic amines and polypeptide hormones.

  • Track 16-1Familial syndromes
  • Track 16-2Gastroenteropancreatic
  • Track 16-3Carcinoid tumors
  • Track 16-4Pancreatic neuroendocrine tumors

People with diabetes are more likely to develop congenital heart disease and have a greater chance to have heart attack or a stroke.  Person with diabetes can protect their heart and health by managing blood glucose, blood pressure and cholesterol. High blood sugar in body eventually damages blood vessels and the nerves that control heart.  Diabetic patients have more chances to develop heart diseases.

  • Track 17-1High blood pressure
  • Track 17-2Too much LDL (“bad”) cholesterol
  • Track 17-3High triglycerides

Biochemical Genetics involves testing and determining inherited metabolic disease, monitoring of treating, and distinguishing heterozygous carriers from non-carriers by metabolite and enzymatic analysis of physiological fluids and tissues in patients. Hereditary metabolic disorders are tested by extremely specialized and fragmented activity, and mostly by research-oriented scientists.

  • Track 18-1Inborn errors of metabolism
  • Track 18-2Malabsorption
  • Track 18-3Malnutrition disorders

Stem cell-derived pancreatic islet transplantation is a β-cell replacement therapy which involves transplantation of isolated islets from donor pancreas to receiver, for the treatment of insulin-deficient diabetes. Once they are transplanted, the islets start producing insulin and actively regulate blood glucose levels. It was observed that 70% of patients who received an islet cell transplant no longer needs insulin after one year and may not need it in the future. Some of the benefits of Islet Transplantation are

  • Track 19-1Improved blood glucose levels
  • Track 19-2Less need or no need for insulin injections to manage diabetes
  • Track 19-3Fewer or no episodes of severe hypoglycaemia

Cardiometabolic syndrome (CMS) is a group of metabolic dysfunctions that are mainly characterized by insulin resistance, impaired glucose tolerance, dyslipidaemia, hypertension, and central adiposity. World Health Organization and the American Society of Endocrinology now recognized CMS as a disease entity. Patients with CMS have more chances to die from coronary heart disease, heart attack or stroke. Cardio metabolic programs and therapeutic strategies that combine diet and exercise prescriptions help to reduce cardiometabolic risk factors.  Treatment strategies include

  • Track 20-1Moderate physical activity
  • Track 20-2Weight reduction or Weight-Loss Surgery
  • Track 20-3Blood pressure control
  • Track 20-4Correction of dyslipidaemia
  • Track 20-5Glycaemic

Prevention and management metabolic syndrome requires addressing several conditions. One can improve overall cardiovascular health and conditions that lead to metabolic syndrome by eating healthier, being physically active, and losing weight.

  • Track 21-1Smoking and metabolic syndrome
  • Track 21-2Physical activity and metabolic syndrome
  • Track 21-3Metabolic syndrome and weight control
  • Track 21-4Influence of diet on metabolic syndrome

Management of metabolic syndrome mainly involves changing lifestyle, changing diet and exercise habits. Evidences show that following proper diet, exercise, and pharmacologic interventions might inhibit the progression of metabolic syndrome to diabetes mellitus.

  • Track 22-1Pharmacologic Therapy
  • Track 22-2Hyperglycemia treatment
  • Track 22-3Triglyceride treatment
  • Track 22-4Preventive cardiovascular treatment
  • Track 22-5Complementary and alternative medicine

Medicinal Plants serves as effective agents in treatment of metabolic disorders as they have biologically active substances. There are more than 1200 medicinal plants that are useful to treat diabetes and also target other risk factors accompanied with metabolic syndrome, including hypercholesterolemia and hypertension. Herbal medicines are useful in reducing waist circumference, blood glucose, blood lipids, and blood pressure. Each metabolic risk factor is associated with one another, and collectively increases the risk to promote atherosclerotic cardiovascular illness.

  • Track 23-1Cinnamon
  • Track 23-2Russian tarragon
  • Track 23-3Bitter melon
  • Track 23-4Fenugreek
  • Track 23-5Grape seed
  • Track 23-6Soybean

The term Diabetes technology is used to refer the hardware, devices, and software that diabetic people can use to help manage blood glucose levels, reduce the risk of diabetes and improve quality of life. Recent technology has extended to include hybrid devices that monitor glucose and deliver insulin. If Diabetes technology used appropriately, it can improve the quality of life and health of people with diabetes.  But, the complexity and quick change of the diabetes technology can also become a barrier to patient and provider implementation.

  • Track 24-1Insulin Pens
  • Track 24-2Management apps
  • Track 24-3Continuous glucose monitors

Patients with type 1 or type 2diabetes should be more cautious about their health. Diabetic patients may experience more complications if they get affected with corona virus. Few reports have shown that about 25% of people who were affected with coronavirus had diabetes. High blood sugar level in the body of diabetic patients weakens the immune system and makes body more vulnerable to coronavirus and can ultimately lead to death. High blood sugar levels weaken the immune system and make it less possible to fight off infections. Corona virus can even increase the risk for diabetes complications like diabetic ketoacidosis (DKA). Therefore if a diabetic patient gets affected by new coronavirus they should check their blood sugar levels more often than usual, take more fluids, and drink water often. To reduce your chance of getting infected:

  • Track 25-1Keep your distance from other people
  • Track 25-2Maintain good hygiene
  • Track 25-3Keep your blood sugar under control
  • Track 25-4Make a plan in place in case you get sick

Education on diabetes is an integral component of the diabetes management and care as diabetes needs day-to-day knowledge on nutrition, exercise, monitoring, and medication.  A healthy diet is required for management of diabetes. The target of patient education is to increase their knowledge, develop confidence in them, assisting them to take control of their own condition and integrate effective self-management into their daily lives. Properly planned education can have an effect on health outcomes and can significantly improve quality of life.

  • Track 26-1Nutritional management
  • Track 26-2Weight management
  • Track 26-3Psychosocial adjustment
  • Track 26-4Diabetes disease process
  • Track 26-5Glucose monitoring
  • Track 26-6Education for insulin users and non-insulin users