Diabetic Pathophysiology

Type2 diabetes mellitus is characterized by a both combinations of inadequate insulin secretion by pancreatic beta cells and peripheral insulin resistance. Insulin resistance, which has been associate to proinflammatory cytokines in plasma  and elevated levels of free fatty acids, it leads to decreased glucose transport into muscle cells, elevated hepatic glucose production, and increased breakdown of fat. The major role for excess glucagon cannot be underestimated; indeed, Type2 diabetes (T2D)  is an islet paracrinopathy in which the reciprocal relationship between the insulin-secreting beta cell and the glucagon-secreting alpha cell is lost, which leads to hyperglucagonemia and hence the consequent hyperglycaemia. For type 2 diabetes mellitus (T2DM) to occur, both insulin resistance and inadequate insulin secretion must exist. Generally all overweight or obese individuals have insulin resistance, but diabetes develops only in those individuals who cannot raise insulin secretion to that level so that it can compensate for their insulin resistance. Their insulin concentrations may be high, which results in low level of glycaemia.

  • Acute pancreatitis symptoms
  • Identification of β-cell dysfunction and insulin resistance
  • Differentiation of diabetes by pathophysiology, natural history
  • Clinical features of diabetes mellitus

Related Conference of Diabetic Pathophysiology

November 11-12, 2019

Annual Congress on Diabetes, Metabolism and Obesity

Sydney, Australia
December 04-05, 2019

3rd Annual Congress on Diabetes and Its Complications

Tokyo, Japan
December 9,10,2019

International Congress and Expo on Diabetic Care

Bangkok,Thailand
December 12-13, 2019

Annual Congress on Diabetes and Endocrinology

Dubai, UAE
January 27-28, 2020

Global Summit On Diabetes & Endocrinology

Bangkok, Thailand
March 25-26, 2020

29th World Diabetes & Heart Congress

| Radisson Narita | Tokyo, Japan
March 27-28, 2020

Annual Summit on Metabolomics

Amsterdam, Netherlands
April 17-18, 2020

3rd Global Meeting on Diabetes and Endocrinology

Kualalumpur, Malaysia
June 15-16, 2020

29thEuropean Diabetes Congress

| Barcelona, Spain
August 17-18, 2020

16th World Congress on Endocrinology & Diabetes

| Copenhagen, Denmark
November 16-17, 2020

2nd Asia Pacific Diabetes and Endocrinology Congress

Brisbane, Australia
June 14-15, 2021

diabetic 2021

Abu Dhabi, UAE

Diabetic Pathophysiology Conference Speakers

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