Pathogenesis of Diabetes

Pathogenesis refers to the process by which a condition or disease develops, encompassing factors contributing to its onset, progression, and maintenance. In diabetes mellitus, characterized by elevated blood sugar levels, pathogenesis involves either insufficient insulin secretion or a combination of insulin resistance and inadequate insulin production. Type 1 diabetes, commonly seen in both children and adults, results from the immune system's attack on pancreatic beta cells responsible for insulin production. Conversely, insulin resistance is a primary metabolic abnormality leading to the development of type 2 diabetes. This condition arises from a series of pathophysiologic changes, each posing a risk to normal glucose regulation.

 

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