Statins & Atherosclerosis

Statins are a class of drugs used to lower LDL cholesterol and reduce the risk of cardiovascular events.

Subtopics:

  • How they work: Inhibiting HMG-CoA reductase, reducing cholesterol production.
  • Types: Atorvastatin, simvastatin, rosuvastatin.
  • Side effects: Muscle pain, liver damage, diabetes risk.
  • Alternatives: Ezetimibe, PCSK9 inhibitors, lifestyle changes.

Atherosclerosis is a condition where plaque builds up inside the arteries, leading to narrowed and hardened arteries, and increasing the risk of heart disease and stroke.

Subtopics:

  • Causes: High cholesterol, high blood pressure, smoking.
  • Symptoms: Often asymptomatic, chest pain, shortness of breath.
  • Diagnosis: Blood tests, imaging, stress tests.
  • Treatment: Lifestyle changes, medications, surgery.

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